
At a daily dose of 6 g or more inhibits the synthesis of prothrombin in the liver and increases the prothrombin time. It is effective in primary prevention of cardio-vascular system and secondary prevention of myocardial infarction. Reduces mortality and risk of myocardial infarction in unstable stenocardia. Reduces aggregation, platelet adhesion and thrombus formation through suppression of synthesis of thromboxane A2 in platelets. Analgesic effect is due to both central and peripheral effects.
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Reduction of prostaglandins (mainly E1) in the thermoregulation center leads to a decrease in body temperature due to expansion of blood vessels of the skin and increase perspiration. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid which is a precursor of prostaglandins which play a major role in the pathogenesis of inflammation, pain and fever. It has anti-inflammatory, analgesic and antipyretic effect, and inhibits platelet aggregation. There is an additional general information about this medication active ingredient aspirin (acetylsalicylic acid): Indications, usages and classification codes: General Information Acetylsalicylicum Acidum forms, composition and dosages: Acetylsalicylicum Acidum by Boiron in case of emergency / overdoseĪcetylsalicylicum Acidum companies and manufacturers:.Acetylsalicylicum Acidum by Boiron drug interactions.Using during pregnancy and breastfeeding.

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